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Overview
Mid-Level

Head of Product/Portfolio Management

Confirmed live in the last 24 hours

Genetix Biotherapeutics

Genetix Biotherapeutics

Compensation

$263,000 - $323,000/year

Somerville, Massachusetts
On-site
Posted April 9, 2026

Job Description

 

About Genetix Biotherapeutics

At Genetix Biotherapeutics every role has meaning, every team member is respected, and every day is a chance to make a difference. When you join Genetix, you're not just landing a new role, you become part of a company that's pursuing curative gene therapies to give patients and their families more days. We are doers, thinkers and collaborators who embrace and live by our values:

Our innovation is rooted in the diversity of our teams and results are achieved through cooperation and the integration of multiple viewpoints. This is personal and we approach every challenge with radical care.

SUMMARY

The Head of Product/Portfolio Management  is a strategic leader for Genetix’ two FDA approved genetic therapies for the treatment of hemoglobinopathies. You will be responsible for establishing the long-term product strategy while enabling teams to achieve execution of lifecycle management plans. You will provide cross-functional leadership across drug development and lifecycle management execution to maximize long-term value for two commercial stage products. You will drive achievement of product goals and advancing Genetix’s leadership in transforming lives through curative therapies. The ideal candidate will be a strategic leader well-versed in drug development and commercial executuion and a strong influencer who can integrate effectively while aligning stakeholders across different functions and levels of the organization. Reporting to the Chief of Staff and Head of Product Leadership, you will champion critical portions of Genetix’s leading assets with significant executive visibility and potential for patient impact.

RESPONSIBILITIES

  • Lead the cross-functional team consisting of senior leaders in Commercial, CMC, Regulatory, Medical, and Clinical, responsible for setting and achieving product vision and strategy
  • Incorporate the long-term vision to develop, optimize, and execute lifecycle management plans
  • Drive the development and execution of the integrated cross-functional strategic and operational product plan and timelines
  • Integrate cross-functional perspectives, ensuring technical rigor, emerging data, competition, and the evolving landscape in key markets are incorporated routinely to inform product direction
  • Partner with functional leads and senior leadership to set product goals aligned with corporate goals
  • Foster strong cross-functional team performance, empowering the team while driving alignment, accountability, prioritization, and timely decision making to deliver on product goals
  • Proactively anticipate issues and ensure contingency plans are put in place; identify barriers and problem-solve to mitigate them; identify opportunities and how to capture them
  • Establish clear product communications and deliver critical updates between teams and senior leaders, ensuring strategic alignment and awareness of changes to strategy or timelines
  • Partner with corporate communications and the Executive Team to develop product communication strategies, positioning, and messaging
  • Drive innovation and maximize long-term value creation by challenging the status quo

QUALIFICATIONS

  • 10+ years of industry experience with 5+ years leading drug development programs/products or in life sciences consulting
  • BA/BS degree required, advanced degree preferred (MBA, PharmD, PhD, MD)
  • Deep understanding of drug development & commercialization
  • Cell and gene therapy, rare disease, and hemoglobinopathy experience strongly preferred
  • Fully and consistently demonstrates strong communication skills across all levels and functions – able to succinctly summarize complex issues (verbally and in writing) to move team forward
  • An authentic leader who builds and maintains strong relationships and trust, with exceptional ability to influence key stakeholders at all levels in a matrix environment
  • Ability to inspire, empower and motivate teams without direct authority to cultivate high performance by creating an environment that invites diverse p
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