Senior / Principal Machine Learning Scientist

What You Will Contribute To Altos

As a Senior or Principal Machine Learning Scientist, you will play a prominent role in developing generative AI/ML models for multi-modal, multiscale biology from virtual cells to agentic target assessment.  We are looking for a hands-on, creative, and collaborative individual to join our multidisciplinary team of scientists and engineers focused on transforming how we treat aging and disease. The successful candidate will thrive in a fast-paced environment that emphasises teamwork, transparency, scientific excellence, originality, rigor, and integrity.

Responsibilities

• Pioneer novel machine learning methodologies and statistical frameworks (e.g., generative models, causal inference, diffusion models, and advanced transformer architectures) to address fundamental challenges in cell health and rejuvenation
• Contribute to setting the long-term technical vision and research strategy for a core domain (e.g., multi-modal data fusion, perturbation modeling) within the Institute of Computation
• Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
• Design, implement, and optimize large-scale machine learning systems using modern frameworks (e.g., PyTorch, JAX) and  agile practices
• Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters to handle terabytes of multi-modal biological data
• Develop robust approaches for multi-modal data integration and cross-domain mapping to extract actionable biological insights
• Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
• Lead the full ML development lifecycle from theoretical conception and data strategy through model development, training, and evaluation
• Act as a key technical mentor to Machine Learning Scientists and Engineers, raising the bar for scientific rigor and model robustness across the organization.

Who You Are

• Proven track record leveraging machine learning to solve real-world problems;
• Expertise in one or more of the following: generative models, language models, computer vision, bayesian inference, causal reasoning & inference, transfer & multi-task learning, diffusion models, graph neural networks, active learning, cooperative agents
• Experience writing production-quality code with modern machine learning frameworks such as PyTorch, TensorFlow, JAX, or similar
• Experience with multi-GPU and distributed training at scale
• A team player who thrives in collaborative environments and is committed to enabling colleagues to reach their full potential through giving and requesting feedback focussed on professional growth
• Able to advise others across the wider function / company on cutting edge practices and approaches to enable the science / research. Desire to constantly expand your skillset and knowledge. Keen to learn more about biology, computational science, and medicine;
• Inspired by the Altos mission of restoring cell health and resilience to reverse disease, injury, and age-related disabilities.

Minimum Qualifications

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