Senior Associate Scientist, Upstream Development for Protein Development and Manufacturing

Confirmed live in the last 24 hours

Vaxcyte

San Carlos, California, United States

On-site

Posted April 1, 2026

Job Description

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

Vaxcyte is looking for a highly motivated and skilled individual to join Vaxcyte’s Vaccine Product Development organization as a Sr Associate Scientist in the Protein Development and Clinical Manufacturing group. The successful candidate will play a crucial role in designing, implementing, and optimizing automation solutions to establish high throughput fermentation process development workflows. The successful candidate will have the following skills and qualities:

Proven experience in designing, programming, and implementing laboratory automation systems
A passionate researcher with a knack for technology innovation to improve performance and efficiency
An exceptional team player who works seamlessly with others, speaks up, and remains focused on achieving the best results to achieve company goals.
Strong organizational and planning skills.

Essential Functions:

Be part of the Ambr operation team and execute high throughput upstream process development experiments.
Design and develop automation solutions for liquid handling, sample preparation and analysis workflows.
Collaborate with Vaxcyte Benchling to enable efficient data capture from automated processes.
Diagnose and troubleshoot technical issues related to automation hardware, software, and protocols.
Author SOPs (standard operating procedure) and train laboratory personnel on the proper operation, maintenance, and troubleshooting of automation systems.

Requirements:

BS in Chemical Engineering or Chemistry/Biochemistry with 5+ years of relevant Pharma/Biotech industry experience, or MS in Chemical Engineering or Chemistry/ Biochemistry with 3+ years of relevant Pharma/Biotech industry experience.
Strong understanding of laboratory workflows in biotech process development.
Familiarity with various automation platforms and technologies, such as liquid handling robots, robotic arms, and plate readers. Experience with Tecan Fluent, Biomek i-series, and/or Ambr 250HT system is a plus.
Knowledge of data analysis and visualization tools.
Excellent problem-solving skills and attention to detail.
Effective communication skills and the ability to collaborate with cross-functional teams.

Reports to: Senior Scientist, Upstream Development for Protein Development & Manufacturing

Location: San Carlos, CA

Compensation:

The compensation package will be competitive and includes comp

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