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Overview
Senior

Senior Software Engineer, .NET

Confirmed live in the last 24 hours

GeneDx

GeneDx

Compensation

$165,000 - $175,000/year

Remote
Remote
Posted March 13, 2026

Job Description

Summary

As a public and profitable company, we have ambitious plans to scale and enhance our products and services. We’re looking for Senior Software Engineers who can design and deliver high-quality solutions, collaborate effectively across teams, and contribute to meaningful improvements in our platform. Senior engineers at GeneDx focus on owning significant components, contributing to architectural discussions, and delivering reliable, well-tested software.

Job Responsibilities

As a Senior Software Engineer, you'll work on advancing our technology platform and building software products that make a meaningful impact. You will contribute to medium- to large-scale technical efforts, mentor junior engineers, collaborate with cross-functional partners, and deliver robust, scalable solutions aligned with our business objectives.

Day to day tasks may include:

  • Dive into unfamiliar code to troubleshoot or add a new feature
  • Participate in feature development of larger projects
  • Technically lead smaller projects
  • Participate in Support tasks, including off-hours and weekend on-call rotations.
  • Propose technical designs, considering standard patterns, tradeoffs, and maintainability
  • Provide thorough and meaningful code reviews
  • Work with legacy as well as novel code bases
  • Prototype, develop, and debug new features
  • Implement and maintain DevOps cloud patterns

 People Manager

  • No

 Education, Experience, and Skills

  • Proficiency in at least 3 software languages, with a demonstrated ability to quickly learn new ones as needed. 
  • 6+ years of software engineering experience, including significant experience in: 
  • .NET Framework and .NET (Core/6+), C# 
  • SQL Server (schema design, performance tuning, migration strategies) 
  • Message queues, ideally MSMQ in production 
  • Demonstrated experience in modernizing legacy applications into cloud‑native microservices and event-driven architectures. 
  • Strong understanding of troubleshooting and maintenance of systems running on a Windows platform 
  • Ability to understand system performance metrics and translate them into actionable improvement tasks 
  • 3+ Experience with front-end applications using modern frameworks (React highly desired, but Vue, or Angular are acceptable). 
  • Experience with data modeling using multiple database and storage types. 
  • 5+ years experience designing and deploying resilient and scalable large scale and distributed services in the cloud using Docker and Kubernetes (e.g. AWS, GCP, Azure, OCI).   
  • Applied knowledge of multiple architectural paradigms. 
  • Bonus points for: 
  • Prior healthcare / health tech experience, or experience in other regulated industries, particularly with data privacy and compliance requirements. 

Bonus points for: 

  • Prior healthcare / health tech experience, or experience in other regulated industries, particularly with data privacy and compliance requirements 

Certificates, Licenses, Registrations

  • None

Physical Demands

 This is a sedentary role requiring prolonged periods of sitting while working at a computer. Physical demands include:

  • Sitting for extended periods (up to 8 hours per day)
  • Repetitive use of hands and fingers for typing and mouse operation
  • Visual acuity for reading computer screens
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