Senior Director, Clinical Development Scientist

We are currently seeking a dedicated and strategically minded Clinical Scientist Senior Director to join our Clinical Development team at Absci. In this pivotal role, you will help translate Absci’s AI-powered drug design into successful drug development programs. This position is ideal for a Senior Director who brings substantive experience in both clinical development and medical affairs. Absci is bringing potentially revolutionary medicines to fulfill unmet patient needs with a dedicated group of experienced team members who embrace working in multiple functions. 

In this important position role, your accountability spans a range of clinical science deliverables for the development program(s) at large as well as individual clinical trials.  Given Absci’s paradigm-creating approach to drug development, contributing to medical affairs strategy and  execution are important components of the position. 

You will leverage your deep background in clinical trial design/execution, medical data oversight, and scientific communication and KOL engagement to ensure our development programs generate high-quality, decision-ready data while building the scientific foundation needed to support our pipeline as it advances toward commercialization. The successful candidate will readily incorporate AI tools  and technology into daily practice to efficiently achieve mission objectives.

Responsibilities:

• Able to function independently with respect to key deliverables with close internal and external stakeholder collaboration.
• Develop expertise in assigned therapeutic areas to serve as a clinical and scientific subject-matter expert for assigned therapeutic area and indication, providing hands-on oversight of protocol execution and clinical data quality to enable decision ready outcomes.
• Engage clinical investigators and study sites to ensure timely and  quality study execution.
• Participating in Investigator meeting planning and execution and assist with site initiation as needed.
• Be a leading voice in ideation of study designs, protocols, charters, publication plans, publication concepts and associated deliverables to fulfill Absci’s clinical development and medical affairs objectives .
• Support investigators, site staff, CROs/ CRAs on study protocol and related questions.
• Work closely with medical monitors on proactive data review, systematically identifying trends, safety signals, and data quality issues in collaboration with clinical operations under an established data monitoring plan.
• Collaborate with a cross-functional team to drive protocol development and governance approval, authoring and reviewing study design, endpoints, eligibility criteria, and related documents; ensure integrity of protocols throughout the trial lifecycle.
• Partner cross-functionally to translate clinical strategy into study concept documents, protocols, and related regulatory facing materials, ensuring alignment with Absci’s development objectives and Good Clinical Practice (GCP) standards.
• Proven ability to build and maintain strong relationships and contribute to interactions with external key opinion leaders to optimize clinical programs (e.g. advisory boards, individual engagements, steering committees, etc.). Experience in