Associate Scientist, Host Cell Protein (HCP) Analytics

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Associate Scientist to join our Product Biochemistry group, supporting our Host Cell Protein (HCP) analytical program. In this role, you will focus on polyclonal antibody purification, ELISA method development, and related reagent generation activities that underpin our HCP impurity monitoring strategy across biologics programs.

This position offers the opportunity to play a key role in enabling high-quality analytical support for process development, CMC, and regulatory filings, contributing to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Shift Requirements: Full-time, standard business hours
• Location: On-site laboratory setting
• Flexibility & travel: Minimal to no travel; on-site presence required to support laboratory operations

What you'll do:

• Purify polyclonal antibodies from rabbit/goat bleeds immunized with host cell protein antigens, using affinity chromatography and other standard purification workflows
• Optimize and streamline purification protocols to improve yield, purity, reproducibility, and throughput
• Support ELISA method development, qualification, and troubleshooting for HCP detection and quantitation
• Prepare, aliquot, and manage critical reagents (antibodies, conjugates, standards, buffers) to ensure consistent assay performance
• Document all experimental work in the electronic laboratory notebook (ELN) in accordance with defined procedures and departmental standards, and provide documentation upon request to support internal reviews, tech transfer, or regulatory submissions
• Collaborate cross-functionally with process development, QC, and analytical teams to align on reagent needs and assay performance criteria
• Contribute to continuous improvement of laboratory workflows and best practices

The environment and physical rhythms of this role:

• This is a hands-on, on-site laboratory role centered on protein purification and immunoassay work, requiring rigorous attention to detail and consistent documentation practices.
• Flexibility to work independently, manage multiple tasks in parallel, and collaborate effectively within a team-oriented environment is required.

Let's find out if we're a fit:

Must-haves:

• BS/MS in Biochemistry, Chemistry, Molecular Biology, or a related life science discipline
• Hands-on experience with protein purification (affinity chromatography, e.g., Protein A/G, antigen-affinity columns; AKTA or equivalent FPLC systems preferred)
• Working knowledge of ELISA and general immunoassay techniques
• Ability to work independently, manage multiple tasks in parallel, and maintain rigorous attention to detail
• Excellent written and verbal communication skills; team-oriented mindset

Preferred / nice-to-haves:

• Prior ELN experience
• Strong documentation habits

Thrive today. Grow tomorrow.

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

 

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$93,900.00 - $153,300.00