About the role

Aplyr's Quick Take

This role is for a Principal Software Engineer focused on developing AI health solutions at Microsoft. You'll be hands-on in coding, collaborating with researchers and designers, and responsible for the entire feature development process. It's an individual contributor role with a strong emphasis on user experience and technical excellence.

Good fit

Ideal candidates have significant experience in software engineering, particularly in AI or health tech, and are self-motivated problem solvers. A collaborative mindset and a passion for user-centric design will help you thrive here.

Worth noting

The position requires a commitment to in-office work starting in 2026, which may be a downside for remote work advocates. Additionally, there's an expectation to contribute to team-building efforts, which may appeal to those looking to take on leadership responsibilities without formal management roles.

Overview

At Microsoft AI, our health team is on a mission to help millions of users better understand and proactively manage their health and wellbeing. We’re responsible for ensuring that Microsoft AI’s models and services are useful, trusted and safe across diverse customer health journeys.

We’re assembling a world-class team of builders with backgrounds in healthcare, big tech, and frontier AI research labs. Our goal is to translate cutting-edge research—like MAI-DxO (microsoft.ai/new/the-path-to-medical-superintelligence)—into transformative products for millions of users across copilot.com and Microsoft’s consumer ecosystem.

We’re looking for engineers who are self-starters, care deeply about user experience, and take pride in solving real customer needs. You’ll collaborate in a fast-paced, iterative environment to bring innovative technology to life, with safety, reliability, and scale front and centre.

We’re hiring across multiple domains: backend, web, mobile, and GenAI. If you have a strong technical spike in one or more of these areas and a proven track record of crafting high-impact user experiences, we’d love to hear from you.

Microsoft’s mission is to empower every person and every organization on the planet to achieve more. As employees we come together with a growth mindset, innovate to empower others, and collaborate to realize our shared goals. Each day we build on our values of respect, integrity, and accountability to create a culture of inclusion where everyone can thrive at work and beyond.

Starting January 26, 2026, MAI employees are expected to work from a designated Microsoft office at least four days a week if they live within 50 miles (U.S.) or 25 miles (non-U.S., country-specific) of that location. This expectation is subject to local law and may vary by jurisdiction.

Responsibilities

Collaborate with AI researchers, product managers, and designers to bring a world-class AI health companion to the world.
Own the end-to-end development of features, from ideation and specification through to deployment and iteration.
Design, build, and optimize production-grade code, delivering robust features within a much larger existing architecture.
Work independently across a wide range of our stack, shipping delightful user experiences.
Ensure resilience, maintainability, and security above all else.
Build the hiring pipelines, onboarding frameworks, or software development best practices as needed to scale an engineering team around you.
Guide peers, contributing to a culture of technical excellence and continuous improvement.

Qualifications

Required Qualifications:

Bachelor's or Higher Degree in Computer Science, or related technical discipline AND strong software engineering experience with coding in languages/frameworks including, but not limited to, C#, C, C++, Java, Python, Rust, Typescript, Swift, Kotlin.
Demonstrated expertise building products at scale, with domain expertise in one or more of distributed systems, cloud infrastructure, web, mobile, GenAI.
Experience collaborating in cross functional teams, working through ambiguity to deliver high quality products.
Have 0 to 1 experience with a bias towards shipping and learning, while balancing a high-quality bar.
Proven ability to collaborate and contribute to a positive, inclusive work environment, fostering knowledge sharing and growth within the team.

Preferred qualifications:

Experience in healthcare technology, particularly with regulated medical devices.
Passionate about conversational AI and its deployment.
Demonstrated written and verbal communication skills with the ability to work closely with cross-functional teams, including product managers, designers, and other engineers.
Passion for learning new technologies and staying up to date with industry trends, best practices, and emerging technologies and patterns in AI.
Experience developing and improving evaluation methodologies for assessing quality of LLM-based products.

This position will be open for a minimum of 5 days, with applications accepted on an ongoing basis until the position is filled.

Microsoft is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, color, family or medical care leave, gender identity or expression, genetic information, immigration status, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran or military status, race, ethnicity, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable local laws, regulations and ordinances. If you need assistance with religious accommodations and/or a reasonable accommodation due to a disability during the application process, read more about requesting accommodations.

Aplyr's read

Microsoft is a technology giant shaping global computing, attracting talent interested in innovation and impact across software, cloud, and AI sectors.
Synthesized from recent postings & public sources

What's promising

•Strong commitment to innovation in AI and cloud computing.
•Diverse range of roles from technical to managerial, offering career growth.
•Financially stable with a robust global presence and market influence.

What to watch

•Complex organizational structure can slow decision-making processes.
•High competition for roles may limit entry-level opportunities.
•Potential for work-life balance challenges in high-demand positions.

Why Microsoft

•Pioneer in personal and business computing with a legacy of innovation.
•Extensive global reach with a diverse workforce and inclusive culture.
•Leader in integrating AI into mainstream software and cloud services.

Aplyr’s read is generated by AI from public sources. Was it useful?

About Microsoft

Microsoft

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MSFT$390.34-1.77%

Microsoft is a global technology company that develops, licenses, and supports a wide range of software products, services, and devices. Known for its Windows operating system and Office productivity suite, Microsoft has a significant impact on personal and business computing worldwide.