Associate Director, Clinical Pharmacology

Confirmed live in the last 24 hours

Eikon Therapeutics

Jersey City, NJ

On-site

Posted April 22, 2026

Job Description

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position

We are seeking an enthusiastic Associate Director, Clinical Pharmacology to join our growing Clinical Research & Development organization and build Modeling and Simulation in the Clinical Pharmacology group. The modeling and simulation activities include NCA, population PK/PD, disease progression, statistical and physiologically based PK (PBPK) modeling, allometric scaling, quantitative system pharmacology (QSP), clinical trial simulations, literature meta-analysis, machine learning/deep learning, and other state-of-the-art quantitative techniques. The candidate will support Clinical Pharmacology Project Leads for the use of quantitative approaches to describe the relationship between drug exposure and response, and to select and defend first in human dose, RP2D, and labeled dose during regulatory interactions. This role will require a minimum of 3 days a week of onsite presence (or more as business needs require) in New Jersey office (Jersey City) to ensure effective management, operational excellence, and delivery of clinical studies and to support the expected significant team growth & collaboration.

About You

You have a passion for innovation, independence, an entrepreneurial spirit, and a strong desire to learn and grow with the best professionals in the industry.

What You’ll Do

Support Clinical Pharmacology Project Leads in analyzing data from preclinical, clinical and stand-alone Clinical Pharmacology studies.
Utilize basic and advanced modeling and simulation techniques to undertake comprehensive Exposure-Response analysis.
Generate and interpret pharmacokinetic/pharmacodynamic (PK/PD) models to inform dose selection and regimen optimization.
Undertake diverse scaling approaches to design optimal dosing regimens for First-In-Human and special populations (e.g. pediatrics).
Conduct biopharmaceutics data analyses (e.g. dissolution performance) with the objective of translating in vitro formulation performance to in vivo formulation performance in humans.
Organize, execute, and report M&S independently, as well as present findings in a clear and concise manner to support decision-making.
Plan, write, and revie