Scientist II, Cancer Pharmacology, Translational Research

Confirmed live in the last 24 hours

Revolution Medicines

Compensation

$160,000 USD

Redwood City, California, United States

Hybrid

Posted May 1, 2026

Job Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a Scientist II in the Cancer Pharmacology team within the Translational Research group, in the Biomedical Discovery Research Department, you will:

Contribute to advancing RAS(ON) inhibitor programs by applying cancer pharmacology and tumor biology expertise, with a focus on mechanistic understanding of RAS biology.
Design, execute, and interpret in vivo efficacy and PK/PD studies (internally and via CROs) to support forward and reverse translation of RAS(ON) inhibitors
Collaborate with the cross-functional quantitative modeling group, providing data, biological context, and critical evaluation to support translational PK/PD modeling (no requirement for hands-on mathematical model experience).
Analyze, interpret, and communicate data clearly to internal teams and external scientific audiences.
Maintain high-quality documentation, protocols, and data integrity.

Required Skills, Experience and Education:

Ph.D. in pharmacology or cancer biology, or a related discipline with direct relevance to oncology drug development.
2+ years of relevant postdoc or industry experience in cancer drug discovery and development.
Solid knowledge of tumor biology and RAS signaling pathways
Demonstrated experience in designing, executing and analyzing in vivo experiments with oncology disease models.
Working knowledge of PK and PK/PD relationships, with the ability to analyze and interpret data.
Rigorous and detail-oriented with proven excellence in experimental design, data analysis, data management, and presentation.
Excellent written and verbal communication skills. Able to effectively communicate results to non-specialist and specialist audiences.
Thrives in a collaborative team setting and is driven by a desire to be innovative in a dynamic and fast-paced environment.

Preferred Skills:

Familiarity with RAS biology and RAS-targeted therapies
Experience with designing and executing PKPD studies in tumor models.
An understanding of preclinical to clinical translational concepts desired.
Strong track record of research productivity as evidenced by high-quality, impactful publications.
A strong theoretical understanding of the core concepts, assumptions, and limitations associated with PK/PD mathematical modeling.

#LI-Hybrid #LI-NE1

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

Base Pay Salary Range

$128,000—$160,000 USD

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