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Sr Machine Learning Engineer

AmgenAmgen·Biotechnology

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Posted

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01

About the role

Career Category

Engineering

Job Description

Position Overview

The GCF5 Sr Machine Learning Engineer is the senior technical leader for the Agentic & ML Platform pillar. They define and socialize platform standards and patterns, lead multi-team delivery, mentor GCF4 engineers, and translate scientific needs into scalable ML/agentic platform designs. They own pillar-level adoption, reliability, and SLA/SLO outcomes, and influence cross-team engineering quality.

This role reports to the GCF7 leader and partners closely with peer GCF5 domain leads across SCIP to ensure cohesive, scalable platform evolution.

Core Responsibilities

  • Own the ML and agentic platform technical roadmap within SCIP.
  • Design and operationalize reusable ML/agentic infrastructure components enabling repeatable deployment.
  • Define evaluation harnesses and model release gates.
  • Establish monitoring, rollback, and observability practices for production ML systems.
  • Implement guardrails and operational controls for safe agentic workflows.
  • Define reproducibility standards and artifact versioning practices.
  • Lead architecture reviews for ML platform evolution.
  • Mentor engineers and elevate ML engineering rigor.
  • Partner with research stakeholders to translate AI use cases into scalable platform capabilities.

Core Competencies

  • Deep expertise in the assigned pillar (Agentic & ML Platform) (Agentic‑ML) with evidence of standard‑setting and reuse.
  • Systems design at scale (ML); performance, security, and observability fundamentals.
  • Product/engineering thinking: road mapping, prioritization, and outcome‑oriented delivery.
  • Stakeholder influence across science, engineering, and governance forums; crisp written/verbal communication.

Core Success Measures

  • Adoption rate of standardized ML platform components.
  • Evaluation coverage across supported ML use cases.
  • Reduction in model regressions and production ML incidents.
  • Time-to-deploy new ML use cases.
  • Reproducibility rate of experiments and deployments.
  • Reduction in safe-use escalations.

Key Relationships

  • Collaborates with GCF6 Group Lead and cross‑functional leaders (R&D/PD/Dev).
  • Mentors and develops GCF4 Data and Software Engineers, partners with platform, data, ML, and research teams.
  • Interfaces with governance (architecture, security, compliance) and vendor/partner teams.

Decision Authority

  • Approve designs within the pillar; define and waive standards/patterns with rationale.
  • Recommend buy‑vs‑build; commit pillar resources to meet SLAs/SLOs; escalate risks.
  • Prioritize pillar backlog and roadmap in alignment with strategy and OKRs.

Qualifications

Basic Qualifications:

  • BS+8 / MS+6 / PhD in CS/Engineering/Data disciplines.
  • Demonstrated production delivery experience in ML/agentic platforms at scale.
  • Demonstrated literacy in a relevant scientific domain (e.g., biology, chemistry, therapeutic discovery).

Preferred Qualifications:

  • Depth in the assigned pillar (Agentic & ML Platform).
  • Kubernetes and continuous integration/continuous delivery (CI/CD) at scale; observability, performance tuning, and security-by-design.
  • Evidence of standard‑setting and cross‑team influence; mentoring experience.

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Skills & Tags

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Aplyr's read

Amgen is a biotechnology leader focused on innovative therapeutics in oncology, cardiovascular, and inflammation, attracting professionals in science, engineering, and data analytics.

Synthesized from recent postings & public sources

What's promising

  • Strong focus on cutting-edge biotechnology and human therapeutics.
  • Diverse career opportunities in scientific, engineering, and data roles.
  • Commitment to addressing serious health conditions like cancer and cardiovascular disease.

What to watch

  • Highly competitive industry with constant innovation demands.
  • Regulatory challenges in developing and marketing new therapies.
  • Potential for high-pressure work environment due to ambitious goals.

Why Amgen

  • Pioneering in biologic therapies with a focus on serious diseases.
  • Robust pipeline of innovative drugs in various therapeutic areas.
  • Global presence with a strong emphasis on research and development.

Aplyr’s read is generated by AI from public sources. Was it useful?

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About Amgen

Amgen is a leading biotechnology company that discovers, develops, manufactures, and delivers innovative human therapeutics. The company focuses on areas such as oncology, cardiovascular disease, and inflammation.

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