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Postdoctoral Fellow – Human Genetics & Cardiometabolic Disease

AmgenAmgen·Biotechnology

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About the role

Career Category

Postdoctoral

Job Description

What You Will Do

Let's do this. Let's change the world.

In this vital role, you will advance our understanding of the genetic and biological mechanisms underlying cardiovascular and cardiometabolic disease through the application of human genetics, functional genomics, and computational biology. Working within Amgen Research, you will leverage large-scale human genetic datasets and emerging genomic technologies to identify novel disease pathways and therapeutic opportunities.

This position is ideal for a highly motivated scientist interested in translating genetic discoveries into biological insights. The successful candidate will work at the intersection of human genetics, data science, and disease biology, integrating diverse genomic and molecular datasets to investigate the functional consequences of genetic variation and uncover mechanisms that influence human health and disease.

The fellow will have the opportunity to collaborate with experts across human genetics, computational biology, cardiovascular biology, and therapeutic discovery, while pursuing innovative and impactful research questions in a highly collaborative environment.

Key responsibilities include:

  • Analyze and integrate large-scale human genetic datasets to identify genes, pathways, and biological mechanisms associated with cardiovascular and cardiometabolic traits.

  • Apply computational and statistical approaches to investigate the functional consequences of genetic variation across diverse populations.

  • Utilize functional genomics, single-cell technologies, and systems biology approaches to understand how genetic variation influences cellular and molecular processes.

  • Integrate multiple layers of genomic and molecular data to prioritize therapeutic hypotheses and uncover disease-relevant regulatory networks.

  • Develop and apply innovative analytical approaches to connect human genetic findings with disease biology.

  • Collaborate with multidisciplinary teams spanning genetics, computational biology, molecular biology, and therapeutic discovery.

  • Present research findings at internal and external scientific meetings and publish results in high-impact peer-reviewed journals.

  • Contribute to the broader scientific mission of translating human genetic insights into novel therapeutic strategies.

This is a four-year fellowship within the Amgen Research & Development Postdoctoral Program, designed to provide advanced scientific training and career development opportunities for outstanding early-career researchers.

What We Expect of You

We are all different, yet we all use our unique contributions to serve patients. The Postdoctoral Fellow we seek is a scientist with these qualifications.

Basic Qualifications

Doctorate degree (PhD) completed prior to the start date from an accredited college or university in Human Genetics, Statistical Genetics, Computational Biology, Bioinformatics, Genomics, Biomedical Sciences, Molecular Biology, or a related scientific discipline.

Preferred Qualifications

  • Strong record of scientific achievement as demonstrated through peer-reviewed publications and presentations.

  • Experience working with large-scale human genetic datasets, including genome-wide association studies, sequencing studies, population biobanks, or related resources.

  • Expertise in computational analysis of genomic, transcriptomic, proteomic, or other multiomic datasets.

  • Familiarity with statistical genetics, functional genomics, systems biology, or gene regulatory network analysis.

  • Experience with single-cell genomic technologies and integrative data analysis approaches.

  • Proficiency in computational programming and data analysis using tools such as Python, R, or similar languages.

  • Demonstrated ability to develop innovative approaches to address complex biological questions.

  • Strong written and verbal communication skills.

  • Ability to work effectively in a collaborative, multidisciplinary research environment.

  • Passion for scientific discovery and a strong interest in translating human genetic findings into biological and therapeutic insights.

What You Can Expect From Us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being.

The Amgen Postdoctoral Program provides fellows with the opportunity to conduct innovative research in a world-class biotechnology environment while receiving mentorship from scientific leaders across multiple disciplines. Fellows are encouraged to publish their findings, present at leading scientific conferences, and build the skills necessary for successful careers in academia, biotechnology, or the pharmaceutical industry.

At Amgen, you will join a collaborative scientific community committed to advancing human health through breakthrough discoveries and innovative medicines. You will have access to cutting-edge technologies, unique human genetics resources, and a network of researchers dedicated to translating science into meaningful therapies for patients.

Join us and transform the lives of patients while transforming your career.

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Salary Range

81,178.40USD -109,829.60 USD
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Aplyr's read

Amgen is a biotechnology leader focused on innovative therapeutics in oncology, cardiovascular, and inflammation, attracting professionals in science, engineering, and data analytics.

Synthesized from recent postings & public sources

What's promising

  • Strong focus on cutting-edge biotechnology and human therapeutics.
  • Diverse career opportunities in scientific, engineering, and data roles.
  • Commitment to addressing serious health conditions like cancer and cardiovascular disease.

What to watch

  • Highly competitive industry with constant innovation demands.
  • Regulatory challenges in developing and marketing new therapies.
  • Potential for high-pressure work environment due to ambitious goals.

Why Amgen

  • Pioneering in biologic therapies with a focus on serious diseases.
  • Robust pipeline of innovative drugs in various therapeutic areas.
  • Global presence with a strong emphasis on research and development.

Aplyr’s read is generated by AI from public sources. Was it useful?

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About Amgen

AMGN$350.53-1.31%

Amgen is a leading biotechnology company that discovers, develops, manufactures, and delivers innovative human therapeutics. The company focuses on areas such as oncology, cardiovascular disease, and inflammation.

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