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Postdoctoral Fellow, Structural Biology, Hsu Lab

GenentechGenentech·Biotechnology

Compensation

$100,000 - $106,500/year

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Posted

53 days

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About the role

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.

The Opportunity:

A Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Peter Hsu in the Department of Structural Biology at Genentech to answer fundamental questions in both chromatin biology and ubiquitination pathways using biochemical and structural biology tools.

The Hsu Lab works on the biochemical and structural mechanisms of large, multi-subunit protein complexes, with an emphasis on chromatin regulatory factors and E3 ubiquitin ligases involved in key cellular processes. In this role, you will have access to state-of-the-art structural biology and biophysical equipment and facilities, including a well-equipped cryoEM core for both single particle and tomography applications. In addition, you will have opportunities to collaborate with other labs both within Genentech and in academia, and present your work at conferences.

Who You Are:

  • Ph.D. with a proven track record of creativity, rigor, and success in structural biology, biochemistry, or a related field, as exemplified by first author publication(s) in high impact journals.

  • Successful experience with expression and purification of multi-protein complexes from multiple sources is required.

  • Experience with X-ray crystallography and/or single-particle cryoEM is required.

  • Independent and capable of designing, executing, and troubleshooting complex experiments to answer challenging scientific questions.

  • A strong collaborative spirit to work with others in a team to bring projects to fruition is needed.

  • Strong oral and written communication skills are required.

Preferred Qualifications:

  • Successful examples of structural determination by single particle cryoEM and/or X-ray crystallography.

  • Experience with chromatin and/or ubiquitin biochemistry.

  • Experience with protein engineering, biophysical methods for protein-protein and protein-nucleic acid interactions, or assay development.

 

For information about the Hsu lab, please go to:

https://scholar.google.com/citations?user=FiSzWjAAAAAJ&hl=en&authuser=1

The expected salary range for this position based on the primary location of South San Francisco California is $100,000 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

Postdoc Program

Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.

The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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Aplyr's read

Genentech pioneers in biotechnology, focusing on innovative treatments for serious diseases, attracting professionals dedicated to advancing medical science.

Synthesized from recent postings & public sources

What's promising

  • Genentech is a leader in biotechnology with a strong focus on innovative drug discovery.
  • The company offers diverse roles, from machine learning to medical science liaisons, indicating a broad scope of opportunities.
  • Genentech's commitment to serious medical conditions ensures meaningful work impacting patient lives.

What to watch

  • The competitive biotech industry may pressure Genentech to maintain rapid innovation.
  • High specialization in roles could limit career flexibility for employees.
  • Genentech's focus on serious diseases may involve high-stakes projects with significant pressure.

Why Genentech

  • Genentech integrates advanced AI in drug discovery, setting it apart in the biotech field.
  • The company's ecosystem approach to roles supports localized healthcare solutions.
  • Genentech's pioneering work in oncology and rare diseases distinguishes its research focus.

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About Genentech

Genentech is a biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.

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