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Senior
Senior Director, CMC Technical Operations, siRNA Therapeutics
Confirmed live in the last 24 hours
Alector
Compensation
$240k - $270k/per-year-salary
South San Francisco, CA
On-site
Posted February 27, 2026
Job Description
Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.
As the Senior Director, CMC Technical Operations, siRNA Therapeutics, you are a senior technical leader advancing siRNA programs from late discovery through clinical development and toward commercialization. You will serve as the CMC technical lead across internal teams and external partners, ensuring robust, scalable, and phase-appropriate manufacturing processes for siRNA drug substance and drug product.
This is an individual contributor role with broad cross-functional influence. You will report to the Vice President of Technical Operations and partner closely with Research, Process Development, Analytical Development, Regulatory, Quality, and CDMOs to deliver high-quality siRNA therapeutics in a dynamic biotech environment.
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