Senior IT Business Systems Analyst, SAP Supply Chain

Confirmed live in the last 24 hours

Vaxcyte

Compensation

$163,000 - $190,000/year

San Carlos, California, United States

On-site

Posted March 18, 2026

Job Description

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

Vaxcyte is undergoing a major ERP transformation, moving to SAP S/4HANA to support its rapid growth and upcoming transition to Commercial Operations. The IT SAP Supply Chain Senior Business Systems Analyst (BSA) will play a critical role in bridging Supply Chain and IT, ensuring successful implementation, stabilization, and ongoing optimization of SAP S/4HANA Supply Chain capabilities. This position requires strong functional expertise in SAP Supply Chain functionalities, deep understanding of contract manufacturing processes, and experience in complex ERP implementation projects.

Essential Functions:

Support the implementation and stabilization of SAP S/4HANA Supply Chain modules in a regulated environment.
Collaborate with Supply Chain, Manufacturing, Quality, and IT teams to design future-state processes aligned with Vaxcyte's CDMO business model.
Assist in data mapping, migration, cleansing, and validation during cutover and post-go-live activities.
In-depth knowledge of SAP S/4HANA systems and integration techniques with third-party planning systems.
Expertise with agile methodology, global deployments, and data migration planning.
Experience working in GxP validated and SOX regulated systems.
Configure and maintain SAP Supply Chain modules including Materials Management (MM), Master Data, Subcontracting & External Processing, Batch Management, and Forecast Consumption & Demand Planning.
Assist with the integration points with FI (Financial Accounting) & CO (Controlling)
Support end-to-end planning flows from demand through manufacturing and supply execution.
Excellent verbal and written communication skills, with the ability to effectively communicate complex technical concepts to non-technical stakeholders.
Work closely with Supply Chain stakeholders (Planning, Procurement, Finance) to capture requirements.
Translate business needs into functional specifications for SAP configuration.
Help develop and document business process flows.
Support complex planning scenarios where capacity, lead times, and execution are controlled by external CDMO partners.
Develop and execute test plans for SAP Supply Planning processes.
Support User Acceptance Testing (UAT) and resolve issues promptly.
Ensure validation readiness and maintain audit trail expectations in compliance with regulatory requirements.
Training & Change Management
Create training materials and deliver sessions for Supply Chain users.
Provide ongoing support post go-live.
Ensure compliance with GxP standards and Life Sciences industry requirements.