About the role

Aplyr's Quick Take

This role is for a Staff Site Reliability Engineer focused on ensuring the reliability and scalability of GRAIL's cloud-native platform. You'll be hands-on with infrastructure engineering while also influencing cross-functional teams and driving standards across the organization.

Good fit

Ideal candidates have significant experience in site reliability or DevOps, with strong technical skills and a collaborative mindset. This role suits those who thrive in fast-paced, mission-driven environments and enjoy mentoring others.

Worth noting

The position requires full-time onsite work in Menlo Park, which may be a drawback for remote workers. Additionally, the role has a strong focus on cross-team influence, which could be a unique opportunity for those looking to expand their leadership skills.

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a Staff Site Reliability / DevOps Engineer to lead the reliability, scalability, and security of our cloud-native platform. This role operates at the intersection of infrastructure engineering, platform strategy, and organizational leadership, supporting systems that power large-scale data processing and cutting-edge cancer detection technologies.

You will define and drive infrastructure standards across teams, represent reliability and performance in architecture decisions, and build systems that scale well beyond your direct ownership. This is a highly technical, high-impact role combining hands-on engineering with cross-functional influence and mentorship.

Onsite Expectations You will work on-site full-time at our office located in Menlo Park, California. Beginning in Fall 2026, you will work at our new headquarters in Sunnyvale, California.

Skills & Tags

ai devops data

Aplyr's read

GRAIL is at the forefront of healthcare innovation, leveraging genomic technology for early cancer detection, attracting talent in engineering, science, and market access.
Synthesized from recent postings & public sources

What's promising

•GRAIL's focus on early cancer detection addresses a critical need in healthcare.
•The company is backed by significant investment, supporting research and development.
•Recent hiring in diverse roles indicates growth and expansion in operations.

What to watch

•The biotechnology sector is highly competitive, with rapid technological advancements.
•Regulatory challenges in healthcare can impact timelines and product launches.
•GRAIL's success heavily depends on the accuracy and reliability of its technology.

Why GRAIL

•GRAIL uses cutting-edge genomic technology for non-invasive cancer detection.
•The company has a strong focus on integrating data science with healthcare.
•GRAIL's mission-driven approach attracts professionals passionate about impactful healthcare solutions.

Aplyr’s read is generated by AI from public sources. Was it useful?