Senior Mechanical Engineer, Miniaturized Sensing Platforms

Confirmed live in the last 24 hours

CZ Biohub

Chicago, IL (Onsite)

On-site

Posted April 21, 2026

Job Description

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

The Diagnostics team develops next-generation sensing technologies for real-time molecular monitoring in living systems. We bring together engineers, chemists, biologists, and translational scientists to create wearable and implantable platforms that enable high-impact applications in healthcare, therapeutics, and disease monitoring.

The Opportunity

We are seeking a Senior Mechanical Engineer to lead the design and development of miniaturized sensing systems for wearable and implantable medical devices. This person will play a critical role in translating early-stage prototypes into robust, manufacturable products by driving the mechanical design of housings, connectors, enclosures, microdevice assemblies, and packaging solutions.

This is a highly cross-functional role that sits at the intersection of engineering, biology, materials science, and product development. The engineer will work closely with scientists and external manufacturing partners to develop compact, high-performance sensing systems that can operate reliably in demanding biological environments.

What You'll Do

Lead the mechanical design and development of wearable, implantable, and miniaturized sensing platforms for biomedical applications
Design and prototype components, connectors, enclosures, fixtures, and packaging solutions for sensor systems and associated electronics
Work closely with multidisciplinary teams to integrate mechanical, electrical, biological, and materials requirements into a manufacturable product
Collaborate with external vendors and manufacturing partners to source, fabricate, and refine high-precision components and assemblies
Conduct prototyping, testing, failure analysis, and design optimization to improve reliability, manufacturability, and long-term device performance

What You'll Bring

PhD in Mechanical Engineering, Biomedical Engineering, Materials Engineering, or a related discipline
At minimum 2+ years of professional experience
Strong industrial experience in medical device development, preferably involving wearable devices, implantable systems, or miniaturized sensing technologies
Expertise in CAD tools such as SolidWorks, Creo, or Fusion 360 and experience designing precision mechanical systems
Experience with medical-grade materials, hydrogels, soft materials, connectors, packaging, and biocompatible assemblies
Strong communication skills and experience working with external vendors, contract manufacturers, and multidisciplinary technical teams

Compensation

The Chicago, IL base pay range for a new hire in this role is $162,000 - $202,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.