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Overview
Mid-Level

VP/SVP Total Rewards & People Operations

Confirmed live in the last 24 hours

Flagship Pioneering

Flagship Pioneering

Compensation

$300,000 - $400,000/year

Cambridge, MA USA
On-site
Posted April 21, 2026

Job Description

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond. 

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

Position Overview

Flagship Pioneering is seeking an experienced and strategic Vice President or Senior Vice President, Total Rewards and People Operations to lead the design, management, and evolution of Total Rewards programs and key people infrastructure across our ecosystem. The scope of this role spans compensation, executive compensation, equity, benefits, people operations, and people analytics for Flagship and its portfolio of companies.

This is a highly visible leadership role requiring deep expertise in compensation strategy and private-company equity, as well as the ability to operate effectively across a complex, fast-paced, and highly matrixed environment. The ideal candidate will bring strong executive presence, sound judgment, and the ability to translate business strategy into scalable people programs that support growth, innovation, and organizational effectiveness.

This leader will oversee an established team across Compensation, Benefits, People Operations, and People Analytics, and will be expected to shape a modern, market-relevant Total Rewards philosophy, refine equity and incentive structures, advance benefits strategy, and drive people insights that support executive decision-making.

Key Responsibilities

Total Rewards Strategy and Leadership

  • Lead the strategy, design, and ongoing evolution of Flagship’s global Total Rewards philosophy across compensation, executive compensation, equity, benefits, and other reward programs. 
  • Serve as the principal architect of rewards strategy, recommending program direction to senior leadership and ensuring alignment with business priorities, talent strategy, and financial objectives. 
  • Develop and refine salary structures, incentive frameworks, equity guidelines, and market positioning approaches across a global footprint. 
  • Oversee job architecture and leveling governance in support of internal equity, talent management, and scalable compensation decision-making. 
  • Guide annual compensation planning processes, including merit, bonus, promotion, and other pay actions, in partnership with HR, Finance, and business leadership. 
  • Partner closely with Talent Acquisition and HR Business Partners on executive and broad-based offer strategy, market competitiveness, and internal equity. 
  • Lead the continued evolution of executive compensation and broad-based equity strategy across Flagship and applicable portfolio companies. 

Equity and Incentive Design

  • Provide strategic leadership for complex equity and long-term incentive programs, including private-company equity struc
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