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Overview
Mid-Level

Manufacturing Technician

Confirmed live in the last 24 hours

Nautilus Biotechnology

Nautilus Biotechnology

San Carlos
On-site
Posted March 20, 2026

Job Description

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are hiring a Manufacturing Technician to join our growing team. This technician will support the assembly and build of our instrument platform. This role will focus on hands-on assembly of complex electromechanical systems including mechanical structures, fluidic systems, and internal electrical wiring within a complex instrument chassis. The Manufacturing Technician will play a critical role in executing prototype and pilot builds, supporting the transition from engineering development to scalable manufacturing. The ideal candidate is comfortable working in a fast-paced development environment and has experience assembling complex scientific or electromechanical instrumentation.

Responsibilities

  • Perform hands-on assembly of complex electromechanical instruments

  • Assemble mechanical chassis, structural components, and internal subassemblies

  • Install and route fluidic systems, including tubing, manifolds, pumps, and valves

  • Install and route electrical wiring and harnesses within instrument enclosures

  • Integrate mechanical, electrical, and fluidic subsystems within the instrument chassis

  • Execute engineering prototype builds, design verification builds, and pilot production builds

  • Follow detailed work instructions and assembly procedures

  • Verify correct installation and alignment of components during assembly

  • Escalate assembly issues or deviations to engineering or operations teams

  • Support troubleshooting and rework activities when required

  • Complete required manufacturing documentation including Device History Records (DHR), build travelers, traceability records

  • Record serial numbers and part traceability information

  • Document deviations or observations during builds

  • Provide redlines or suggested improvements to assembly instructions

  • Provide feedback to engineering and operations teams regarding build challenges or assembly issues

  • Document observations that may improve manufacturability or assembly efficiency

  • Support continuous improvement of assembly processes during pilot builds

Requirements

  • 3–7+ years of experience assembling complex electromechanical systems

  • Experience working with mechanical assemblies, fluidics, and electrical wiring

  • Experience working in prototype, NPI, or pilot manufacturing environments

  • Preferred industries include:

    • Biotechnology / life sciences instrumentation

    • Medical devices

    • Analytical instrumentation

    • Semiconductor equipment

    • Aerospace instrumentation

Additional Requirements

  • Strong attention to detail and assembly quality

  • Ability to work independently after initial training

  • Comfortable working in a fast-paced development environment

  • Ability to identify and escalate build issues quickly

  • Strong communication skills and ability to work cross-functionally with engineering teams

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