About the role
The Opportunity
The Strategic Change Leadership Lead, Director is a key member of the Strategy & Activation team, working across Commercial, Medical, and Government Affairs (CMG). This role drives the successful adoption of strategic initiatives and organizational capabilities by applying deep expertise in change leadership, organizational effectiveness, and team effectiveness.
As a trusted advisor to senior leadership, you will shape and execute change strategies that enable cross-functional alignment, innovation, and sustainable performance. You’ll foster a culture of resilience, adaptability, and continuous improvement, ensuring that change becomes a lasting competitive advantage.
Key Responsibilities
Strategy Development & Execution
Serve as a strategic advisor and thought leader, guiding transformational and incremental change within CMG functions.
Balance strategic partnership with hands-on execution, leading teams through the design and delivery of change initiatives.
Conduct diagnostic assessments to identify change readiness, gaps, and opportunities, and develop mitigation strategies to drive sustainable results.
Change Capability & Culture Activation
Lead the activation of CMG-wide strategic initiatives that embed shared mindsets and behaviors, ensuring adoption and sustained impact with senior leadership support.
Embed core behavior shifts that bring CMG’s Value to life by cultivating the Change Leadership Capabilities curriculum — focused on:
Role Modeling Change (responsibility and accountability, decision making, shifting from “me” to “we”)Leading Change (creating psychological safety, managing productive conflict, addressing resistance)
Communicating Change (connecting hearts and minds, leveraging change accelerators).
Stakeholder Engagement & Communication
Build and maintain strong relationships with senior leaders, department heads, and key stakeholders
across the CMG teams to ensure alignment and buy-in for change initiatives.
Actively partner with Learning & Skill Development (L&SD), People & Culture (P&C), and Communications partners to manage the sequence and flow of information, training, and accountability.
Leverage an indirect network of change champions across the organization to scale change actions and narratives and support change adoption and sustainability.
Implementation and Monitoring
Monitor the effectiveness of change management initiatives, track progress against metrics, and provide regular updates to senior leadership, demonstrating business impact.
Establish mechanisms for continuous improvement, capturing lessons learned, feedback, and data-driven insights to refine approaches and enhance future change initiatives.
Who you are
You have a Bachelor’s degree in Business Administration, Organizational Development, Organizational Psychology, or a related field.
10+ years of progressive experience in organizational development, strategic initiative execution, transformation programs, or business operations within a complex, matrixed environment, with a strong emphasis on leading large-scale organizational change.
Deep expertise in organizational change management, championing change in a positive way with demonstrated experience in leading cross-functional cultural initiatives from strategy to implementation.
Proven track record of sustained organizational impact and successfully executing change management strategies in complex and rapidly changing environments.
Proficient in coaching senior leadership teams and demonstrated expertise and experience in team coaching or systemic practice (e.g., Certified Coach, Systemic or Team Coach preferred).
Preferred Qualifications
Master’s degree or professional certification in Change Management (e.g., CCMP, Prosci ADKAR, Kotter's Change Management Model).
Experience in the Pharmaceutical, Biotech, or similar regulated industries is a plus.
This position requires as presence at our South San Francisco, CA Genentech Campus
Relocation benefits are not available on this job posting
The expected salary range for this position based on the primary location of South San Francisco, CA is $156,500/yr to $290,700/yr . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
#LI-CM4
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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Aplyr's read
Genentech pioneers in biotechnology, focusing on innovative treatments for serious diseases, attracting professionals dedicated to advancing medical science.
What's promising
- •Genentech is a leader in biotechnology with a strong focus on innovative drug discovery.
- •The company offers diverse roles, from machine learning to medical science liaisons, indicating a broad scope of opportunities.
- •Genentech's commitment to serious medical conditions ensures meaningful work impacting patient lives.
What to watch
- •The competitive biotech industry may pressure Genentech to maintain rapid innovation.
- •High specialization in roles could limit career flexibility for employees.
- •Genentech's focus on serious diseases may involve high-stakes projects with significant pressure.
Why Genentech
- •Genentech integrates advanced AI in drug discovery, setting it apart in the biotech field.
- •The company's ecosystem approach to roles supports localized healthcare solutions.
- •Genentech's pioneering work in oncology and rare diseases distinguishes its research focus.
Aplyr’s read is generated by AI from public sources. Was it useful?
About Genentech
Genentech is a biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.
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