Business Systems Analyst, SharePoint & Collaboration Platforms

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.  

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.  

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. 

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

Business Systems Analyst – SharePoint & Collaboration Platforms

Job Summary

The Business Systems Analyst  (BSA) – SharePoint & Collaboration Platforms is responsible for the administration, optimization, and strategic enablement of Flagship Pioneering’s knowledge management and collaboration ecosystem, with a primary focus on SharePoint as the enterprise knowledge platform.

This role combines hands-on SharePoint administration with broader collaboration tooling support (e.g., Slack, Notion, Smartsheet), ensuring systems are well-governed, user-friendly, and aligned with evolving business needs. The BSA serves as a subject matter expert for SharePoint, driving adoption, improving knowledge structures, and enabling scalable, efficient ways of working across the organization. 

Key Responsibilities

SharePoint Administration & Knowledge Management 

• Administer, configure, and maintain SharePoint Online environment, ensuring performance, security, and reliability. 
• Design and manage site architecture, libraries, lists, metadata, and content types to support scalable knowledge management. 
• Establish and enforce governance standards, permissions models, and content lifecycle policies. 
• Develop and optimize knowledge structures (hubs, document management frameworks). 
• Troubleshoot and resolve issues related to access, performance, integrations, and usability. 
• Serve as the primary subject matter expert (SME) for SharePoint across the organization. 

Collaboration Platform Management 

• Administer and support tools such as Slack, Notion, Smartsheet, and other collaboration applications. 
• Partner with teams to design workspaces, templates, and workflows that improve usability and adoption. 
• Monitor system usage and optimize licensing, performance, and configuration. 
• Maintain system documentation, runbooks, and governance guidelines. 

Workflow Automation & Integration

• Design and implement workflows using Power Automate and other automation tools. 
• Support integrations across Microsoft 365 and third-party platforms. 
• Identify opportunities to streamline collaboration and knowledge-sharing processes through automation. 

User Enablement & Adoption

• Lead onboarding, training, and support for SharePoint and collaboration tools. 
• Promote best practices for knowledge organization, content management, and collaboration.