About the role
The research focuses on understanding the novel functions of fusion transcriptional factors in rhabdomyosarcoma. This work is highly mechanistic and translational, leveraging cutting-edge genetic, epigenetic, cellular and pharmacologic tools to inform better therapies using human and genetic models.
Key Responsibilities
Design and conduct experiments investigating the mechanism of chimeric transcriptional factors in regulating gene transcription.
Evaluate preclinical efficacy of immunomodulators and the underlying mechanism.
Collaborate within a multidisciplinary team including cancer biologists and clinicians.
Present findings at national and international meetings and contribute to manuscript preparation and grant proposals.
Qualifications
A Ph.D. (or nearing completion) in molecular biology, cancer biology, biochemistry, developmental biology, immunology, or related fields.
Experience with mouse models, genome editing is a plus.
Excellent communication skills, critical thinking, and a collaborative mindset.
A strong publication record demonstrating scientific rigor and productivity.
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Aplyr's read
St. Jude Children's Research Hospital is a leading pediatric research facility dedicated to treating catastrophic diseases in children, with a strong focus on cancer.
What's promising
- •St. Jude covers all treatment costs, ensuring no family receives a bill.
- •The hospital is a pioneer in pediatric cancer research, contributing to increasing survival rates.
- •It offers diverse roles from research to facilities, catering to a wide range of professional expertise.
What to watch
- •The high-stakes environment may lead to significant pressure and stress.
- •Funding largely depends on donations, which can be unpredictable.
- •Limited public information about career advancement opportunities within the organization.
Why St. Jude Children's Research Hospital
- •St. Jude's research breakthroughs have significantly influenced global pediatric cancer treatment protocols.
- •The hospital's commitment to free care is unparalleled in the healthcare industry.
- •Its global sickle cell disease initiative highlights a strong focus on underserved populations.
Aplyr’s read is generated by AI from public sources. Was it useful?
About St. Jude Children's Research Hospital
St. Jude Children's Research Hospital is a pediatric treatment and research facility focused on children's catastrophic diseases, particularly cancer.
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